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前列腺腫瘤高表達(dá)蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN40236R
  • 中文名稱：
    前列腺腫瘤高表達(dá)蛋白1抗體
  • 英文名稱：
    Rabbit anti-PTOV1 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40236R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40236R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱PTOV1
中文名稱前列腺腫瘤高表達(dá)蛋白1抗體
別    名ACID2; Activator interaction domain containing protein 2; Gcap3; prostate tumor overexpressed 1; Prostate tumor overexpressed gene 1; PTOV 1; PTOV1_HUMAN; Prostate tumor-overexpressed gene 1 protein; PTOV-1; Activator interaction domain-containing protein 2.  



研究領(lǐng)域腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat, 
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
細(xì)胞定位細(xì)胞核 細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PTOV1:61-160/416 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹PTOV1 belongs to the Mediator complex subunit 25 family, PTOV1 subfamily. It may activate transcription and is required for nuclear translocation of FLOT1. PTOV1 promotes cell proliferation. There are three named isoforms.

Function:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Subunit:
Interacts with PTH1R (via N-terminal extracellular domain).

Subcellular Location:
Secreted.

DISEASE:
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Similarity:
Belongs to the parathyroid hormone family.

SWISS:
Q86YD1

Gene ID:
53635

Database links:

Entrez Gene: 53635 Human

Entrez Gene: 84113 Mouse

Entrez Gene: 292888 Rat

Omim: 610195 Human

SwissProt: A4IFC9 Cow

SwissProt: Q86YD1 Human

SwissProt: Q91VU8 Mouse

SwissProt: Q5U2W6 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.