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單氨氧化酶A+B抗體
  • 產品貨號：
    BN40335R
  • 中文名稱：
    單氨氧化酶A+B抗體
  • 英文名稱：
    Rabbit anti-Monoamine oxidase A+B Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規格

    售價

    備注

  • BN40335R-100ul

    100ul

    ￥2360.00

    交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40335R-200ul

    200ul

    ￥3490.00

    交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產品描述

英文名稱Monoamine oxidase A+B
中文名稱單氨氧化酶A+B抗體
別    名Adrenalin oxidase; AOFA_HUMAN; AOFB_HUMAN; Amine oxidase (flavin containing) A; Amine oxidase (flavin containing); Amine oxidase (flavin containing) B; Brunner syndrome; MAO A; MAO; MAO brain; MAO platelet; MAOA; MAOB; Monoamine oxidase A; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type A; Monoamine oxidase type B; Tyramine oxidase.  
研究領域細胞生物  神經生物學  信號轉導  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量60+59kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Monoamine oxidase A+B:131-230/527 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹Monoamine oxidase A and B catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. MAOB preferentially degrades benzylamine and phenylethylamine

Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Subunit:
Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

Subcellular Location:
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

Tissue Specificity:
Heart, liver, duodenum, blood vessels and kidney.

DISEASE:
Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.

Similarity:
Belongs to the flavin monoamine oxidase family.

SWISS:
P21397 P27338

Gene ID:
4128 4129

Database links:
UniProtKB/Swiss-Prot: P21397.1 UniProtKB/Swiss-Prot: P27338.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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