貨號
產品規格
售價
備注
BN41993M-50ul
50ul
¥1486.00
交叉反應:Human,Mouse,Rat 推薦應用:WB,IHC-P
BN41993M-100ul
100ul
¥2360.00
交叉反應:Human,Mouse,Rat 推薦應用:WB,IHC-P
產品描述
英文名稱 | NSE |
中文名稱 | 神經元特異性烯醇化酶單克隆抗體 |
別 名 | Gamma-enolase; Gamma enolase; Neural enolase; Neuron specific enolase; neurone-specific enolase; 2 phospho D glycerate hydrolyase; Eno 2; Eno2; ENO2; ENOG; Enolase 2; Enolase 2 gamma neuronal; Enolase2; Neuron specific enolase; Neuron specific gamma enolase; NSE; ENOG_HUMAN; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; enolase 2, gamma, neuronal. |
研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 15E2 |
交叉反應 | Human, Mouse, Rat, |
產品應用 | WB=1:500-2000 IHC-P=1:100-500 (石蠟切片需做抗原修復) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48kDa |
細胞定位 | 細胞漿 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant human NSE protein: |
亞 型 | IgG |
純化方法 | affinity purified by Protein G |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產品介紹 | This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]. Function: Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. Subunit: Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. Subcellular Location: Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. Tissue Specificity: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. Similarity: Belongs to the enolase family. SWISS: P09104 Gene ID: 2026 Database links: Entrez Gene: 2026 Human Entrez Gene: 13807 Mouse Omim: 131360 Human SwissProt: P09104 Human SwissProt: P17183 Mouse Unigene: 511915 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神經元特異性烯醇化酶(NSE)存在于神經元細胞和神經內分泌組織中,起源于神經內分泌細胞的腫瘤可產生過量的NSE。NSE也是小細胞肺癌的檢測指標,70%左右的小細胞肺癌患者血中NSE升高,而其他組織型肺癌NSE升高的患者僅為10%~20%。 |